RAF Typhoon fighter aircraft have conducted a mission with French aircraft in a combined operation targeting an underground arms cache in Syrian territory used by the IS group, as stated by the UK's MoD.
The facility, located using intelligence, was assessed as storing arms and explosives, the release indicated, and was positioned in mountains just north of the ancient city of Palmyra in Syria's central region.
"Our fighter planes employed Paveway IV guided bombs to strike a several access tunnels down to the facility... initial indications are that the objective was successfully hit," the ministry announced.
There was no indication of any civilian impact in the strike conducted Saturday night and every plane involved made a safe return, the MoD added.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
IS - alternatively referred to as ISIS - established jihadist rule over parts of Iraq and Syria until 2019.
"This operation demonstrates our UK leadership, and commitment to operate in unison with our allies, to eradicate any resurgence of IS and their dangerous and violent ideologies in the area," UK Defence Secretary John Healey said.
RAF aircraft have carried out patrols over Syria to "deter any efforts to regroup" of the group after its military defeat at the climactic battle in Baghuz in 2019, the MoD reported.
"I must thank all the members of the UK armed forces who took part in this mission for their professionalism and their valour," he added. "Including them were thousands of UK service members stationed over Christmas and New Year. This action, to remove terrorist threats who pose a risk to our way of life, highlights how British military are ready to step up, continuously, ensuring Britain's security domestically and powerful internationally."
Last December, the United States armed forces conducted what it described as a "major assault" against Daesh sites in Syria, subsequent to an ambush killed two American soldiers and a civilian interpreter in the Palmyra area.
The United Nations says Islamic State still has an estimated 5,000 to 7,000 fighters in Iraq and Syria.